Targeting cellular pathways in glioblastoma multiforme | Signal Transduction and Targeted Therapy
PI3K and Akt as molecular targets for cancer therapy: current clinical outcomes | Acta Pharmacologica Sinica
IJMS | Free Full-Text | Wnt and PI3K/Akt/mTOR Survival Pathways as Therapeutic Targets in Glioblastoma | HTML
Cells | Free Full-Text | PI3K/AKT/mTOR-Targeted Therapy for Breast Cancer | HTML
Patient-Derived Orthotopic Xenografts and Cell Lines from Pediatric High-Grade Glioma Recapitulate the Heterogeneity of Histopathology, Molecular Signatures, and Drug Response | bioRxiv
A novel PI3K inhibitor XH30 suppresses orthotopic glioblastoma and brain metastasis in mice models - ScienceDirect
PI3K/AKT/mTOR and Ras/Raf/MEK/ERK pathway genes are over-expressed in... | Download Scientific Diagram
Therapeutic strategies of glioblastoma (GBM): The current advances in the molecular targets and bioactive small molecule compounds - ScienceDirect
Recent advances in the use of PI3K inhibitors for glioblastoma multiforme: current preclinical and clinical development | Molecular Cancer | Full Text
A Patient-Derived Glioblastoma Organoid Model and Biobank Recapitulates Inter- and Intra-tumoral Heterogeneity - ScienceDirect
IJMS | Free Full-Text | Molecular Mechanisms of Drug Resistance in Glioblastoma | HTML
Development of a novel preclinical glioblastoma mouse model and therapeutic impact of IRE1 inhibition | bioRxiv
A preclinical orthotopic model for glioblastoma recapitulates key features of human tumors and demonstrates sensitivity to a combination of MEK and PI3K pathway inhibitors. - Abstract - Europe PMC
Frontiers | Small Molecule Inhibitors in Adult High-Grade Glioma: From the Past to the Future
Orthotopic GBM model characterization. (A) Tumor cells were isolated... | Download Scientific Diagram
Novel Therapeutic Venues for Glioblastoma: Novel Rising Preclinical Treatment Opportunities | IntechOpen
PI3Kinase signaling in glioblastoma | SpringerLink
A preclinical orthotopic model for glioblastoma recapitulates key features of human tumors and demonstrates sensitivity to a com
Patient-derived models recapitulate heterogeneity of molecular signatures and drug response in pediatric high-grade glioma | Nature Communications
Combined treatment of orthotopic GBMs with BKM120 and PD0325901 results... | Download Scientific Diagram
The effects of PI3K-mediated signalling on glioblastoma cell behaviour | Oncogenesis
Small Molecule Inhibitors in Adult High-Grade Glioma: From the Past to the Future - Frontiers
Frontiers | Genetic Alterations in Gliomas Remodel the Tumor Immune Microenvironment and Impact Immune-Mediated Therapies
Effects on Cx43, autophagy and the PI3K/Akt/mTOR and MEK/ERK1/2 signal... | Download Scientific Diagram
Genetic biomarkers of drug response for small-molecule therapeutics targeting the RTK/Ras/PI3K, p53 or Rb pathway in glioblastoma | CNS Oncology
PD-L1 confers glioblastoma multiforme malignancy via Ras binding and Ras/Erk/EMT activation - ScienceDirect
Frontiers | Next-Generation in vivo Modeling of Human Cancers
Patient-Specific Orthotopic Glioblastoma Xenograft Models Recapitulate the Histopathology and Biology of Human Glioblastomas In Situ - ScienceDirect
